Abeysinghe P

ORCID: 0000-0001-9354-352X · 4 papers in corpus · active 2020-2025
2025
Journal of extracellular biology ·doi:10.1002/jex2.70084

Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility-related genes represents a significant knowledge gap in understanding post-t…

2023
Scientific reports ·doi:10.1038/s41598-023-32045-1

Aberrant inflammation in the endometrium impairs reproduction and leads to poor fertility. Small extracellular vesicles (sEV) are nanoparticles 30-200 nm in-size and contain transferable bioactive molecules that reflect the parent cell. Hol…

2023
Drug delivery and translational research ·doi:10.1007/s13346-022-01225-3

Exosomes are nano-vesicles (30-150 nm) which may be useful as therapeutic delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the human body and therefore are not prone to immunogenicity effects which woul…

2020
International journal of molecular sciences ·doi:10.3390/ijms21239106

Abnormal uterine function affects conception rate and embryo development, thereby leading to poor fertility and reproduction failure. Exosomes are a nanosized subclass of extracellular vesicles (EV) that have important functions as intercel…