Zheng X

Xiaojun Zheng,1,* Yu Wang,1,* Haiping Li,1 Juncha Zhang,1 Jun Liu,1 Xihui Zheng,1 Jie Zhang,1 Guangya Fan,1 Yi Sun,1 Bingxian Li,1 Jingyi Jiao,1 Guang Zuo,1 Xisheng Fan,1,2 Yanfen She1,2 1College of Acupuncture-Moxibustion and Tuina…

BACKGROUND: Endometriosis is a chronic gynecological disorder characterized by pain and impaired quality of life (QoL). While pharmacological and surgical options exist, their limitations necessitate complementary strategies. The comparativ…

Ovarian cancer is one of the most lethal gynecological malignancies globally, with significant variations in incidence, prevalence, and outcomes across regions and population subgroups. This study systematically evaluates the global, region…

BACKGROUND: Cervical clear cell adenocarcinoma (CCAC) and cervical endometrioid adenocarcinoma (CEAC) are rare and aggressive non-HPV-associated malignancies. Despite their histological similarities, these subtypes demonstrate distinct biol…

BACKGROUND: Endometriosis (EM) is a disease related to reproductive dysfunction. The mechanism of epigenetic factors (EF) in EM still needs to be studied. Emerging evidence suggests that EF plays a role in the development of EM. However, th…

Juan Du,1 Zimo Li,2 Shujun Chen,2 Xia Zheng,3 Yu Zhang,2 Xingwei Pu,4 Mingya Zhu,2 Xiang Hu51School of Medicine and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Clinical M…

Endometriosis (EMs) is a chronic neuroinflammatory disorder prevalent in women of reproductive age characterized by heterogeneous clinical manifestations, while conventional Western therapies are limited by obvious adverse reactions and uns…

Dysbiosis of the female genital tract microbiota represents a key pathological basis underlying clinical symptoms such as vaginal dryness and dyspareunia, which subsequently contribute to diminished sexual quality of life (QoL) in women. Al…

Recent advancements in tissue clearing and three-dimensional (3D) visualization technologies have enabled subcellular-level examination of entire organs, particularly in complex structures such as the ovary and uterus. Traditional histologi…

OBJECTIVE: Our study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs). METHODS: The study population was sourced from two indepe…

BACKGROUND: The impact of serum vitamin D levels on the success of assisted reproductive technology (ART) among women with polycystic ovary syndrome (PCOS) has not been fully explored. METHODS: This cohort study enrolled 111 patients with …

This review article focuses on the role of choline in ovarian follicular development, regulated by nutrient-epigenetic interactions. Choline, a key feed additive, participates in DNA methylation and steroid hormone synthesis via its methyl …

Infertility has emerged as a significant global health concern. Assisted reproductive technology (ART) assists numerous infertile couples in conceiving, yet some experience repeated, unsuccessful cycles. This study aims to identify the pivo…

OBJECTIVE: To compare the effectiveness and safety of different acupuncture-related therapies combined with pharmacotherapies for treating symptomatic endometriosis. METHODS: A pre-defined search strategy was conducted across eight databas…

BACKGROUND: Infertility represents a prevalent condition affecting the reproductive system. It has a global incidence of approximately 17.5%. Nutritional supplements are increasingly used as complementary therapy for female infertility, tho…

Qiaomei Yang,1,* Jingxuan Hong,2,3,* Xinye Zheng,1,* Xianhua Liu,4 Hao Lin,1 Li Chen,1 Fuchun Zhong,5 Qianhui Zhang,1 Junying Jiang,1 PengMing Sun1 1Department of Gynecology, Fujian Maternity and Child Health Hospital, College o…

BACKGROUND: Adenomyosis is a chronic inflammatory gynecological disorder closely linked with diminished fertility potential that poses significant challenges in pharmacological management. Salvia miltiorrhiza (Danshen, DS), a traditional Ch…

This study aimed to explore potential risk factors for severe endometriosis and to develop a model to predict the risk of severe endometriosis. A total of 308 patients with endometriosis were analyzed. Least absolute shrinkage and selection…

Adenomyosis (AM) is recognized as a complex gynecological and endocrine disorder that contributes to infertility and elevates the risk of pregnancy complications; however, its underlying genetic basis remains unidentified. This study aimed …

Ovarian cancer (OC) remains one of the most lethal gynecological malignancies, largely due to its late-stage diagnosis and high recurrence rates. Chronic inflammation is a critical driver of OC progression, contributing to immune evasion, t…

Adenomyosis (AM) is characterized as a chronic and progressive disorder with limited therapeutic strategies available. Myometrial fibrosis is a prominent pathological feature of AM, yet the underlying molecular mechanisms remain elusive. Th…

The purpose of this review is to evaluate the effectiveness of large animal models in gynecology research and provide future perspectives. Gynecological diseases are diverse and pose a serious threat to women's physical and mental health. I…

BACKGROUND: Studies have found that post-traumatic growth exists in patients with recent hysterectomy. However, previous studies have overlooked heterogeneity within groups. There is a lack of research on whether there are different categor…

BACKGROUND: Opportunistic bilateral salpingo-oophorectomy (BSO) is recommended in women who have undergone a hysterectomy due to gynecological carcinomas and/or in women with genetic indications, especially for women who do not intend to co…

Danggui Shaoyao San (DSS), a classical multi-herbal formulation of traditional Chinese medicine, demonstrates therapeutic potential for Type 2 Diabetes Mellitus (T2DM), Alzheimer's Disease (AD), and Polycystic Ovary Syndrome (PCOS). This re…