Abstract Evidence suggests that clear cell and endometrioid ovarian carcinoma may arise from endometriosis. We previously identified that some endometriosis lesions exhibit a “cancer-like” PD-1/PD-L1 positive staining similar to endometr…
Abstract Evidence suggests that certain histotypes of ovarian carcinoma -mainly clear cell (CCOC) and endometrioid (EOC) carcinoma-may arise from endometriosis (EAOC), although the biological mechanisms underlying this phenomenon remain unc…
Sex cord-like endometrioid carcinoma (SCLEC) is an uncommon entity which may constitute a diagnostic challenge. This study aimed to perform a clinicopathological, immunohistochemical, and molecular reappraisal of ovarian SCLEC. Consecutive …
Abstract Endometriosis represents a pressing medical concern, imposing a relevant burden on patients including potential malignant transformation into endometriosis-associated ovarian cancer (EAOC). Despite the process of cancer development…
BackgroundThe aim of this study was to assess the agreement rate between intraoperative evaluation (IOE) and final diagnosis (FD) in a series of surgically resected endometrial carcinoma (EC), with a preoperative ambiguous or inconclusive d…