Juan Hao

No ORCID on file · 1 paper in corpus

2022

Oncometabolite D-2-hydroxyglutarate - dependent metabolic reprogramming induces skeletal muscle atrophy during cancer cachexia

·doi:10.21203/rs.3.rs-1246702/v1

Abstract Cancer cachexia is characterized by weight loss and skeletal muscle wasting. Based on the up-regulation of catabolism and down-regulation of anabolism, cachexia-associated metabolites and oncometabolites can accumulate in cancer p…