OBJECTIVE: The purpose of this prospective study was to study the association between rotating nightshift work and endometriosis risk within the Nurses' Health Study II. STUDY DESIGN: We found 89,400 women without diagnosed endometriosis a…
The scientific literature on endometriosis specific to the adolescent population is limited, and the existing data are retrospective and descriptive in nature. It is possible that the disease has a different pathophysiology in adolescents, …
BACKGROUND: Infertility and early pregnancy loss are prevalent as is exposure to secondhand tobacco smoke (STS). Previous research has suggested a relationship between STS exposure and early pregnancy loss, but studies have been limited by …
BACKGROUND: Human exposure to polychlorinated biphenyls (PCBs) remains widespread. PCBs have been associated with adverse reproductive health outcomes including reduced fecundability and increased risk of pregnancy loss, although the human …
STUDY OBJECTIVE: To evaluate the efficacy and tolerability of norethindrone acetate (NA) as single-agent hormonal therapy for suppression of endometriosis symptoms in adolescents and young adults. DESIGN: Retrospective study. SETTING: Two…
Endometriosis is a common gynaecological disease associated with severe pelvic pain and sub-fertility. There is considerable debate whether different endometriosis stages represent disease progression, or whether moderate-severe (rAFS III/I…
BACKGROUND: An inverse association between adult body mass index (BMI) and risk of endometriosis has frequently been reported. However, the association between body size during childhood and early adulthood and endometriosis is not as well …
BACKGROUND: Endometriosis is a prevalent but enigmatic gynecologic disorder for which few modifiable risk factors have been identified. Fish oil consumption has been associated with symptom improvement in studies of women with primary dysme…
BACKGROUND: Phthalates are ubiquitous chemicals used in consumer products. Some phthalates are reproductive toxicants in experimental animals, but human data are limited. OBJECTIVE: We conducted a cross-sectional study of urinary phthalate…
Endometriosis is a common gynecological disease associated with pelvic pain and subfertility. We conducted a genome-wide association study (GWAS) in 3,194 individuals with surgically confirmed endometriosis (cases) and 7,060 controls from A…
the conclusion that women with a high fatty acid intake are less likely to undergo a laparoscopy since a high fatty acid intake can reduce menstrual pain. Finally, laparoscopy as a diagnostic tool will pick up also subtle endometriosis and …
BACKGROUND: In the one study examining the relationship, adolescent physical activity was not associated with risk for endometriosis. Case-control studies have shown 40-80% reductions in risk for adult activity, while only an 11% reduction …
BACKGROUND: Regular exercise has been associated with a 40%-80% reduction in risk for endometriosis in several case-control studies. However, women experiencing symptoms prior to their diagnosis may be less likely to exercise than healthy c…
OBJECTIVE: To address the lack of predictors of IVF success by using proteomic biometrics. DESIGN: Experimental study of follicular fluid specimens from a prospective cohort of IVF patients. SETTING: Academic research laboratory and IVF p…
Endometriosis impacts quality of life and productivity. Women may require multiple admissions for surgery and prolonged pharmaceutical treatment with problematic side effects. In 2002, the annual costs of endometriosis in the USA were betwe…
BACKGROUND: Genetic variation contributes to the risk of developing endometriosis. This review summarizes gene mapping studies in endometriosis and the prospects of finding gene pathways contributing to disease using the latest genome-wide …
PURPOSE: To determine the demand and preferences of infertility patients for sex selection for nonmedical reasons, and to investigate the relation between these choices and their demographic and socioeconomic characteristics. METHODS: A cr…