Lacy BE

ORCID: 0000-0002-2778-0786 · 4 papers in corpus
2026
Managing the Diagnostic and Therapeutic Challenges of Irritable Bowel Syndrome.
Gastroenterology & hepatology

The management of patients with irritable bowel syndrome (IBS) remains a common clinical challenge for health care providers. IBS is a prevalent disorder that encompasses a constellation of symptoms that may be caused by a variety of underl…

2024
High-Dimensional Clustering of 4000 Irritable Bowel Syndrome Patients Reveals Seven Distinct Disease Subsets.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association ·doi:10.1016/j.cgh.2022.09.019

Background and aimsIrritable bowel syndrome (IBS) is a pain disorder classified by bowel habits, disregarding other factors that may influence the clinical course. The aim of this study was to determine if IBS patients can be clustered base…

2022
Efficacy and safety of vibegron for the treatment of irritable bowel syndrome in women: Results of a randomized, double-blind, placebo-controlled phase 2 trial.
Neurogastroenterology and motility ·doi:10.1111/nmo.14448

BackgroundPreclinical and clinical studies suggest that β3 -adrenergic receptor activation may be a novel target for treating abdominal pain and gastrointestinal motility dysfunction in patients with irritable bowel syndrome (IBS). This pro…

article 2001
Anasarca and Small Bowel Obstruction Secondary to Endometriosis
Journal of clinical gastroenterology ·doi:10.1097/00004836-200102000-00017

Intestinal involvement by endometriotic tissue occurs in up to 37% of patients with endometriosis. The vast majority of patients do not experience symptoms related to the gastrointestinal tract. In particular, the complications of intestina…