Xin Huang

PURPOSE: Mechanisms of immune dysregulation associated with advanced tumors are relatively well understood. Much less is known about the role of immune effectors against cancer precursor lesions. Endometrioid and clear-cell ovarian tumors p…

Abstract Endometriosis is a largely benign, chronic inflammatory disease that may predispose to some of the ovarian tumors histotypes, collectively called endometriosis-associated ovarian cancers (EAOC). Although it is widely accepted that …

Abstract Introduction: Epithelial ovarian cancer (EOC) is detected in late stages, when mortality is high due to the lack of an effective screening modality. One of the possible accepted precursors for endometrioid, clear cell and low grade…

Abstract Introduction: Endometriosis is a largely benign, chronic inflammatory disease defined by the presence of endometrial-like glands surrounded by stroma. Epidemiologic studies suggest that endometriosis is an independent risk factor f…

PURPOSE: Endometriosis, a largely benign, chronic inflammatory disease, is an independent risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify plasma miRNAs that can be used to differentiate patients w…

We are pleased that our research (1) has generated interest in the scientific community, and we are happy to provide our reply to the comments submitted by Dr. Haifeng Qiu.The major concern addressed by Dr. Qiu is that the upregulation of p…

Abstract Purpose Ovarian cancer is usually diagnosed at a late stage, making it the deadliest gynecological cancer in women. Identification of precursor lesions and development of biomarkers for early diagnoses are currently needed. Endomet…

OBJECTIVES: We aimed to investigate the nature of endometrial stromal sarcoma (ESS) arising from endometriosis. METHODS: The clinical data of 5 patients with ESS arising from endometriosis were reviewed retrospectively. The expression of C…