Kiriaki Papaikonomou

ORCID: 0000-0002-0862-6265 · 2 papers in corpus

2022

Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women.

Genome medicine ·doi:10.1186/s13073-022-01063-5

BackgroundBreast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising pr…

article 2020

Effects of the levonorgestrel intrauterine system on the endometrium after long-term exposure to mifepristone: Secondary outcomes of a randomized controlled trial

·doi:10.1016/j.ejogrb.2020.06.056

ObjectiveLong-term treatment with progesterone receptor modulators (PRM) is associated with a distinct histological entity termed progesterone receptor modulator associated endometrial changes (PAEC). While accumulating evidence implies tha…