Kathleen Groesch

Introduction/Purpose: Endometriosis is a benign gynecological disease which is defined as the implantation of endometrial tissue on the mesenchymal surface of peritoneal organs. This disease is associated with systemic inflammation and sub-…

By Aneesh Chawla, Stacy Parr & 10 more. We hypothesized that socio-economic factors correlate with altered inflammatory profiles (elevated Th17:Treg ratio) and subsequent higher stage and/or grade of EC at the time of surgery.

PROBLEM: Endometriosis is associated with gastrointestinal (GI) and urogenital (UG) microbial dysbiosis in patients with endometriosis (P-EOSIS). Sexual partner exposure may contribute to microbial dysbiosis but has not been studied in P-EO…

INTRODUCTION: Endometriosis is associated with inflammation. We characterized systemic immune populations in patients with endometriosis and identified associations between immune status and therapies (surgical intervention and/or hormonal …

Endometriosis is an estrogen dependent gynecological disease associated with altered microbial phenotypes. The association among endogenous estrogen, estrogen metabolites, and microbial dynamics on disease pathogenesis has not been fully in…

PROBLEM: Endometriosis is defined as growth of endometrial tissue in ectopic locations; it is associated with infertility and chronic pain and affects ~12% of reproductive-aged women. Although inflammation is known to play a key role in end…

Endometriosis is a common gynecological disease, which causes chronic pelvic pain and infertility in women of reproductive age. Due to limited efficacy of current treatment options, a critical need exists to develop new and effective treatm…