Esther Dos Santos

nonrandomized-trial 2023

Should the Treatment of Patients with Repeated Embryo Implantation Failure Be Adapted as a Function of the Endometrial Cytokine Profile? A Single-Center Experience

Biomedicines ·doi:10.3390/biomedicines11030817

Repeated embryo implantation failures (RIF) is a source of distress and frustration for patients and clinicians alike. Today's approaches for treating RIF are largely empirical and have limited effectiveness. The main causes of RIF are poor…

lab-animal 2023

The effect of obesity on uterine receptivity is mediated by endometrial extracellular vesicles that control human endometrial stromal cell decidualization and trophoblast invasion

Journal of extracellular biology ·doi:10.1002/jex2.103

The objectives of the present study were to determine whether obesity impacts human decidualization and the endometrial control of trophoblast invasion (both of which are required for embryo implantation) and evaluate the potential involvem…

lab-animal 2016

Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans

Open biology ·doi:10.1098/rsob.160109

Recurrent spontaneous abortion (RSA) is a common cause of infertility, but previous attempts at identifying RSA causative genes have been relatively unsuccessful. Such failure to describe RSA aetiological genes might be explained by the fac…

other 2012

Adiponectin and leptin systems in human endometrium during window of implantation

Fertility and sterility ·doi:10.1016/j.fertnstert.2011.12.042

OBJECTIVE: To measure the expression of adiponectin, leptin, and their respective receptors in the human endometria of fertile women compared with women with unexplained recurrent implantation failure (IF) during the window of implantation.…