Carvajal J

ORCID: 0000-0001-6875-7825 · 1 paper in corpus

2008

2-methoxyestradiol mediates apoptosis through caspase-dependent and independent mechanisms in ovarian cancer cells but not in normal counterparts.

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108324171

ObjectiveThe estrogen metabolite 2-methoxyestradiol has shown antitumorigenic action in some epithelial tumors. In the present work we investigate its effects in ovarian cancer used alone or in combination with other apoptotic-inducing reag…