Thung S
No ORCID on file
· 6 papers in corpus
· active 2005-2010
Study types
- review 4
- article 1
Condition tags
- endometriosis 5
Top journals
Frequent coauthors
- Utsunomiya H 6
- Bulun SE 6
- Imir G 6
- Hiroki Utsunomiya 5
- Serdar E. Bulun 5
- Lin Z 5
- Gonca İmir 5
- Stephen Thung 5
- Yin P 4
- Zhihong Lin 4
review
2010
Estradiol (E2) stimulates the growth and inflammation in the ectopic endometriotic tissue that commonly resides on the pelvic organs. Several clinical and laboratory-based observations are indicative of resistance to progesterone action in …
review
2010
Loss of progesterone signaling in the endometrium may be a causal factor in the development of endometriosis, and progesterone resistance is commonly observed in women with this disease. In endometriotic stromal cells, the levels of progest…
2007
Pathogenesis and growth of three common women's cancers (breast, endometrium and ovary) are linked to estrogen. A single gene encodes the key enzyme for estrogen biosynthesis named aromatase, inhibition of which effectively eliminates estro…
article
2007
Local estrogen biosynthesis is a major factor in the pathogenesis of endometriosis. Aberrant expression of steroidogenic acute regulatory protein (StAR) and aromatase in endometriotic tissue leads to an up-regulation of estrogen production.…
review
2005
Endometrial tissue from uterine disease-free women does not exhibit aromatase activity. In contrast, aromatase enzyme activity and mRNA levels are readily detectable in endometriosis. PGE2 stimulates both aromatase expression and activity i…
review
2005
A single gene encodes the key enzyme for estrogen biosynthesis termed aromatase, inhibition of which effectively eliminates estrogen production. Aromatase inhibitors successfully treat breast cancer and endometriosis, whereas their roles in…