Andrei E Medvedev

No ORCID on file · 2 papers in corpus
review 2013
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research ·doi:10.1089/jir.2012.0140

Toll-like receptors (TLRs) are germ-line-encoded innate immune sensors that recognize conserved microbial structures and host alarmins and signal expression of MHC proteins, costimulatory molecules, and inflammatory mediators by macrophages…

lab-animal 2012
Journal of immunology (Baltimore, Md. : 1950) ·doi:10.4049/jimmunol.1200202

Asp(299)Gly (D299G) and, to a lesser extent, Thr(399)Ile (T399I) TLR4 polymorphisms have been associated with gram-negative sepsis and other infectious diseases, but the mechanisms by which they affect TLR4 signaling are unclear. In this st…