Klatt NR

No ORCID on file · 3 papers in corpus · active 2010-2025
2025
Common cervicovaginal sequencing methods result in discordant molecular diagnoses of bacterial vaginosis and reveal strain level effects of Gardnerella vaginalis.
npj women's health ·doi:10.1038/s44294-025-00089-5

Bacterial vaginosis (BV) is associated with HIV transmission and pre-term birth, yet the etiology of BV remains unknown. Our analysis addressed that knowledge gap by comparing diagnostic techniques and using Bayesian inference to find speci…

2016
Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract.
PLoS pathogens ·doi:10.1371/journal.ppat.1005889

The mechanism(s) by which bacterial communities impact susceptibility to infectious diseases, such as HIV, and maintain female genital tract (FGT) health are poorly understood. Evaluation of FGT bacteria has predominantly been limited to st…

2010
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
PLoS pathogens ·doi:10.1371/journal.ppat.1001052

The chronic phase of HIV infection is marked by pathological activation of the immune system, the extent of which better predicts disease progression than either plasma viral load or CD4(+) T cell count. Recently, translocation of microbial…