Włodzimierz Sawicki

2024

The Polish Society of Gynecological Oncology Guidelines for the Diagnosis and Treatment of Cervical Cancer (v2024.0).

Journal of clinical medicine ·doi:10.3390/jcm13154351

Background: Recent publications underscore the need for updated recommendations addressing less radical surgery for <2 cm tumors, induction chemotherapy, or immunotherapy for locally advanced stages of cervical cancer, as well as for the sy…

2023

Comparison of Interleukin-6 with Other Markers in Diagnosis of Ovarian Cancer.

Journal of personalized medicine ·doi:10.3390/jpm13060980

The lack of specific symptoms in ovarian cancer delays onset of the diagnostic process. Hence, most cases are recognized in late stages of the disease. The aim of this study was to confirm the role of Il-6 compared to other markers in diagn…

article 2023

Evaluation of Proteasome and Immunoproteasome Levels in Plasma and Peritoneal Fluid in Patients with Endometriosis

International journal of molecular sciences ·doi:10.3390/ijms241814363

Endometriosis is a chronic disease in which the endometrium cells are located outside the uterine cavity. The aim of this study was to evaluate circulating 20S proteasome and 20S immunoproteasome levels in plasma and peritoneal fluid in wom…

2023

Metastases and Recurrence Risk Factors in Endometrial Cancer-The Role of Selected Molecular Changes, Hormonal Factors, Diagnostic Methods and Surgery Procedures.

Cancers ·doi:10.3390/cancers16010179

The presence of metastatic endometrial cancer (EC) is a key problem in treatment failure associated with reduced overall survival rates. The most common metastatic location is the pelvic lymph nodes, and the least common is the brain. The p…

2022

Endometrial Cancer Management in Young Women.

Cancers ·doi:10.3390/cancers14081922

Endometrial cancer (EC) rarely develops in young women. Most cases are associated with known risk factors: BMI > 30, history of Polycystic Ovary Syndrome (PCOs), and race differentiation. The molecular EC classification based on The Cancer …

article 2019

Pre-surgical diagnostic challenges for coincidental three pathologies (endometrial cancer, ovarian serous cyst and endometriotic cyst): case report

·doi:10.1016/j.ejogrb.2018.08.140

2018

Does the Risk of Ovarian Malignancy Algorithm Provide Better Diagnostic Performance Than HE4 and CA125 in the Presurgical Differentiation of Adnexal Tumors in Polish Women?

Disease markers ·doi:10.1155/2018/5289804

AimThis study compared the diagnostic performance of the Risk of Ovarian Malignancy Algorithm (ROMA) and HE4 and CA125 for the presurgical differentiation of adnexal tumors.Material and methodsThis prospective study included 302 patients ad…

article 2016

The role of HE4 and CA125 in differentiation between malignant and non-malignant endometrial pathologies

·doi:10.5603/gp.2016.0088

OBJECTIVES: The aim of the study was to assess the role of HE4 and CA125 in differentiation between malignant and non-malignant endometrial pathologies. MATERIAL AND METHODS: A retrospective study of 87 patients with endometrial pathologies…

2015

Growth factors, silver dressings and negative pressure wound therapy in the management of hard-to-heal postoperative wounds in obstetrics and gynecology: a review.

Archives of gynecology and obstetrics ·doi:10.1007/s00404-015-3709-y

PurposeThe last two decades witnessed the development of numerous innovative regimens for the management of patients with abnormally healing and infected wounds. Growth factors, negative pressure wound therapy (NPWT) and antiseptic dressing…

2015

Hemoperitoneum in a patient with spontaneous rupture of the posterior wall of an unscarred uterus in the second trimester of pregnancy.

BMC research notes ·doi:10.1186/s13104-015-1575-0

BackgroundHemoperitoneum resulting from a rupture of an unscarred uterus is a rare condition. Uterine rupture in patients without evident risk factors is associated with non-specific signs and symptoms that can delay the diagnosis. This is …