Larry Ouderkirk

No ORCID on file · 1 paper in corpus

article 1999

Use of Truncated Areas to Measure Extent of Drug Absorption in Bioequivalence Studies: Effects of Drug Absorption Rate and Elimination Rate Variability on this Metric

·doi:10.1023/a:1018839300168

PurposeTo compare the applicability and accuracy of truncated area (AUCt; where t represents truncated time) versus area to the last quantifiable time point [AUC(O-T)] for assessing bioequivalence. Drugs with either very low or very high in…