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- Benelli E 1
- De Marco G 1
- Ferrarini E 1
- Fruzzetti F 1
- Gianetti E 1
- Orsolini F 1
- Simoncini T 1
- Tonacchera M 1
2021
BackgroundPremature ovarian insufficiency (POI) is an ovarian defect characterized by primary or secondary amenorrhea, hypergonadotropism and hypoestrogenism which occurs before the age of 40 years with a major genetic component. In this st…