Kulke M

ORCID: 0000-0002-2689-2428 · 1 paper in corpus

2021

A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.

Journal of inflammation research ·doi:10.2147/jir.s304787

PurposeAlthough strongly related, the pathophysiological effect of the N34S mutation in the serine protease inhibitor Kazal type 1 (SPINK1) in chronic pancreatitis is still unknown. In this study, we investigate the conformational space of …