Daniel Lai

ORCID: 0000-0001-9203-6323 · 2 papers in corpus · active 2017-2020

Study types

  • article 1
  • other 1

Condition tags

  • endometriosis 2
article 2020
Abstract B09: Single-cell RNA sequencing of normal endometrial organoids uncovers novel cell-type markers for prognostication of primary tumor samples
·doi:10.1158/1557-3265.ovca19-b09

Abstract Endometrial epithelium gives rise to both endometrial and ovarian cancers (of clear-cell and endometrioid subtypes), the latter arising from ectopic endometrium (endometriosis). Endometrial epithelium comprises mainly secretory cel…

other 2017
Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes
Nature genetics ·doi:10.1038/ng.3849

We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in …