Carbone V

ORCID: 0000-0003-4231-2785 · 1 paper in corpus · active 2007

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2007
A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase
Medicinal chemistry (Shariqah (United Arab Emirates)) ·doi:10.2174/157340607782360399

20alpha-hydroxysteroid dehydrogenase (AKR1C1) plays a key role in the metabolism of progesterone and other steroid hormones, thereby regulating their action at the pre-receptor level. AKR1C1 is implicated in neurological and psychiatric con…