Meng TG

ORCID: 0000-0001-8069-0256 · 3 papers in corpus
2026
Cuproptosis causes meiotic metaphase I arrest by disrupting mitochondrial functions in oocytes.
Cell death discovery ·doi:10.1038/s41420-026-03168-x

Proper oocyte maturation is critical for female fertility, yet whether cuproptosis, a recently identified copper-dependent cell death pathway, affects meiotic maturation remains unknown. Here, we show that Cu(II)-elesclomol (ELC-Cu(II)) tre…

2026
The dynamic landscape and conserved regulation of the m6Am and m6A methylomes during the human and mouse oocyte-to-embryo transition.
Nucleic acids research ·doi:10.1093/nar/gkag103

N 6-methyladenosine (m6A) and N6, 2'-O-dimethyladenosine (m6Am) are two RNA modifications that play essential roles in diverse RNA metabolic processes and functions. Despite their importance, the dynamic landscapes and regulatory patterns o…

2018
Mitochondrial regulation of [Ca2+]i oscillations during cell cycle resumption of the second meiosis of oocyte.
Cell cycle (Georgetown, Tex.) ·doi:10.1080/15384101.2018.1489179

Oocyte is arrested at metaphase of the second meiosis until fertilization switching on [Ca2+]i oscillations. Oocyte activation inefficiency is the most challenging problem for failed fertilization and embryonic development. Mitochondrial fu…