Mikala Egeblad

No ORCID on file · 2 papers in corpus

review 2023

NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps

Cancer cell ·doi:10.1016/j.ccell.2023.02.001

Neutrophils are major effectors and regulators of the immune system. They play critical roles not only in the eradication of pathogens but also in cancer initiation and progression. Conversely, the presence of cancer affects neutrophil acti…

2022

Single-cell transcriptome analysis reveals evolutionarily conserved features during the transition from normal breast stromal cells to cancer-associated fibroblasts

·doi:10.1101/2022.05.05.490693

Summary To comprehend cancer-associated fibroblasts (CAFs) origins, single-cell RNA sequencing was conducted on normal and cancerous breast tissue from mice and humans. We found three conserved CAF subtypes, which based on GOterm analysis …