Mariya Petrosyan

No ORCID on file · 2 papers in corpus · active 2018-2023

Study types

  • article 2

Condition tags

  • endometriosis 2
article 2023
iRGD-Targeted Peptide Nanoparticles for Anti-Angiogenic RNAi-Based Therapy of Endometriosis
Pharmaceutics ·doi:10.3390/pharmaceutics15082108

Anti-angiogenic RNAi-based therapy can be considered as a possible strategy for the treatment of endometriosis (EM), which is the most common gynecological disease. Targeted delivery of siRNA therapeutics is a prerequisite for successful tr…

article 2018
Anti-angiogenic treatment of endometriosis via anti-VEGFA siRNA delivery by means of peptide-based carrier in a rat subcutaneous model
Gene therapy ·doi:10.1038/s41434-018-0042-7

Development of gene therapy for endometriosis requires inhibition of vascularization in endometrial lesions. We have previously developed CXCR4 receptor-targeted siRNA carrier L1 and observed efficient RNAi-mediated down-regulation of VEGFA…