Binqing Fu

ORCID: 0000-0002-7713-0001 · 3 papers in corpus
lab-animal 2024
Pyroptotic T cell-derived active IL-16 has a driving function in ovarian endometriosis development
Cell reports. Medicine ·doi:10.1016/j.xcrm.2024.101476

Endometriosis, affecting 6%-10% of women, often leads to pain and infertility and its underlying inflammatory mechanisms are poorly understood. We established endometriosis models in wild-type and IL16KO mice, revealing the driver function …

other 2024
Single-cell transcriptomic analysis of immune cell dynamics in the healthy human endometrium
Biochemistry and biophysics reports ·doi:10.1016/j.bbrep.2024.101802

The microenvironment of the endometrial immune system is crucial to the success of placental implantation and healthy pregnancy. However, the functionalities of immune cells across various stages of the reproductive cycle have yet to be ful…

lab-animal 2022
Estrogen receptor beta promotes endometriosis progression by upregulating CD47 expression in ectopic endometrial stromal cells
Journal of Reproductive Immunology ·doi:10.1016/j.jri.2022.103513

Endometriosis is a common estrogen-dependent gynecological disorder that is characterized by endometrial-like tissue being found at extrauterine sites. Aberrant expression and activation of estrogen receptor beta (ERβ) in ectopic endometriu…