Yasuyuki Toyoda

ORCID: 0000-0001-6727-3511 · 2 papers in corpus
lab-animal 2026
Absorption, distribution, metabolism, and excretion of linzagolix after a single oral dose in rats and monkeys
Xenobiotica; the fate of foreign compounds in biological systems ·doi:10.1080/00498254.2026.2752069

1. Linzagolix is an orally available gonadotropin-releasing hormone antagonist used to treat female-specific diseases, such as uterine fibroids and endometriosis.2. After a single dose of [14C]linzagolix or linzagolix to female rats and mon…

lab-animal 2022
Non-clinical studies indicating lack of interactions between iron/calcium ions and linzagolix, an orally available GnRH antagonist
Xenobiotica; the fate of foreign compounds in biological systems ·doi:10.1080/00498254.2022.2109076

Linzagolix is an orally available gonadotropin-releasing hormone antagonist used to treat sex-hormone-dependent diseases in women. This study aimed to investigate drug-drug interactions between linzagolix and iron/calcium ions in the intend…