Eun‐Ju Lee

ORCID: 0000-0001-9446-1059 · 4 papers in corpus
other 2025
Journal of ovarian research ·doi:10.1186/s13048-025-01722-2

BACKGROUND: Approximately 100,000 human endogenous retroviruses (HERV) are integrated into the human genome. Most HERVs are not expressed; however, transcription within the family HERV-K, a class II beta-retrovirus, occurs in specific cance…

observational 2023
Journal of ovarian research ·doi:10.1186/s13048-023-01098-1

BACKGROUND: The intra-abdominal cavity, surrounded by adipocytes, is the main metastatic site of epithelial ovarian, fallopian tube, and peritoneal cancer. Epidemiological and molecular studies have demonstrated a link between adipose tissu…

observational 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115625841

Endometriosis is a major cause of disability in women, and 40% to 50% of patients experience disease recurrence by 5 years after surgery. This multicenter retrospective cohort study (N = 588) determined the rate and risk factors for recurre…

lab-animal 2013
Molecular human reproduction ·doi:10.1093/molehr/gat091

Mammalian target of rapamycin (mTOR) is known to be a major negative regulator of autophagy. Recent studies have shown that mTOR activity is abnormally increased in endometriotic lesions. In endometriosis, abnormal mTOR activity may contrib…