Lei Gan

ORCID: 0000-0001-8807-0190 · 4 papers in corpus
other 2023
Identification of molecular subtypes and immune infiltration in endometriosis: a novel bioinformatics analysis and In vitro validation
Frontiers in immunology ·doi:10.3389/fimmu.2023.1130738

INTRODUCTION: Endometriosis is a worldwide gynacological diseases, affecting in 6-10% of women of reproductive age. The aim of this study was to investigate the gene network and potential signatures of immune infiltration in endometriosis. …

other 2022
Bioinformatical analysis identifies PDLIM3 as a potential biomarker associated with immune infiltration in patients with endometriosis
PeerJ ·doi:10.7717/peerj.13218

BACKGROUND: Endometriosis is a chronic systemic disease, whose classic symptoms are pelvic pain and infertility. This disease seriously reduces the life quality of patients. The pathogenesis, recognition and treatment of endometriosis is st…

other 2022
Identification and Validation of Three m6A Regulators: FTO, HNRNPC, and HNRNPA2B1 as Potential Biomarkers for Endometriosis
Genes ·doi:10.3390/genes14010086

BACKGROUND: N6-methyladenosine is involved in numerous biological processes. However, the significance of m6A regulators in endometriosis is still unclear. METHODS: We extracted three significant m6A regulators between non-endometriosis an…

lab-animal 2021
Establishment and Mechanism Study of a Primary Ovarian Insufficiency Mouse Model Using Lipopolysaccharide
Analytical cellular pathology (Amsterdam) ·doi:10.1155/2021/1781532

This study is aimed at establishing a lipopolysaccharide- (LPS-) induced primary ovarian insufficiency (POI) mouse model and investigating the underlying mechanism. C57BL/6N female mice were intraperitoneally injected with low-dose LPS (0.5…