Raghvendra K. Dubey

The abnormal growth of oligodendrocyte precursor cells (OPCs) significantly contributes to the progression of glioblastoma tumors. Hence, molecules that block OPC growth may be of therapeutic importance in treating gliomas. 2-Methoxyestradi…

Endometriosis, a painful disorder associated with infertility, is estimated to occur in approximately 7-10% of reproductive age women. Although endometriosis is considered as an estrogen-dependent disease, the role of estrogen metabolites v…

2-Methoxyestradiol (2-ME) is a biologically active metabolite of 17beta-estradiol that appears to inhibit key processes associated with cell replication in vitro. The molecule has been suggested to have potent growth-inhibitory effects on p…

Einleitung: Obwohl die Endometriose eine östrogenabhängige Erkrankung ist, welche nur in Ausnahmefällen außerhalb des Reproduktionsalters auftritt, ist der der Östrogenwirkung zugrunde liegende pathophysiologische Mechanismus bisher nicht g…