Hangyu Chen

ORCID: 0000-0002-9141-2056 · 4 papers in corpus
diagnostic-accuracy 2026
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis
EBioMedicine ·doi:10.1016/j.ebiom.2026.106225

BACKGROUND: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has been widely applied in oncology but remains underexplored for adenomyosis. We aimed to identi…

diagnostic-accuracy 2026
Epigenetic precision diagnostics of traditional Chinese medicine (TCM) syndrome differentiation: a pilot study of atrial fibrillation with qi-yin deficiency syndrome based on 5-hydroxymethylcytosine signatures in extracellular vesicle DNA from plasma
Chinese medicine ·doi:10.1186/s13020-025-01267-y

BACKGROUND: Syndrome differentiation in Traditional Chinese Medicine (TCM) is pivotal to clinical practice and dictates the efficacy of medicinal treatments. However, precision diagnostic models for TCM syndromes, constructed from biomarker…

2025
5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Serve as Potential Biomarkers for Diagnosis and Classification of Adenomyosis
·doi:10.2139/ssrn.5163331
diagnostic-accuracy 2023
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis
·doi:10.21203/rs.3.rs-3253918/v1

Abstract Background: At present, clinical diagnosis and classification of adenomyosis are mainly dependent on MRI or pathological examination, and little research is carried out on molecular biomarkers for the diagnosis and classification o…