Massimo Mischi

OBJECTIVE: To study the impact of laparoscopic niche repair on subendometrial peristalsis in women with a large niche. METHODS: A explorative prospective cohort study that included women with a large niche (residual myometrium ≤ 3 mm), actu…

Adenomyosis is a common gynecological disease, with transvaginal ultrasonography being the first-line imaging method to diagnose it, based on the qualitative morphological uterus sonographic assessment (MUSA). However, the accuracy of diagn…

Objectives: Heavy menstrual bleeding, dysmenorrhea and subfertility are associated with adenomyosis, a benign uterine condition characterised by ectopic endometrium within the myometrium. Currently, diagnosing adenomyosis is challenging. Im…

Adenomyosis, a benign yet serious uterine condition, is highly prevalent but difficult to diagnose and assess using conventional B-mode ultrasound imaging. As the formation of adenomyosis involves angiogenesis and influences local microvasc…

Heavy menstrual bleeding, dysmenorrhea and subfertility are common symptoms that are associated with adenomyosis. However, diagnosing adenomyosis remains challenging, leading to insufficient treatment options. Angiogenesis plays a pivotal r…

OBJECTIVE: To evaluate uterine contractility in patients with adenomyosis compared with healthy controls using a quantitative two-dimensional transvaginal ultrasound (TVUS) speckle tracking method. DESIGN: A multicenter prospective observa…

Study objective: The aim of this study was to characterise the severity of adenomyosis on MRI in infertile women, and to assess if MRI characteristics of adenomyosis severity are associated with worse IVF/ICSI pregnancy outcomes versus male…

Abstract Study question Description of uterine contractility characteristics in adenomyosis patients compared to healthy controls and according to degree of dysmenorrhoea measured by quantitative 2D transvaginal ultrasound (TVUS). Summary a…

Comparison of uterine contractility (UC) in adenomyosis patients (AP) with and without hormonal contraception (HC) compared to healthy controls with HC, measured by transvaginal ultrasound (TVUS). This study is part of an ongoing multicentr…

Abstract Study question Comparison of uterine contractility (UC) in adenomyosis patients (AP) with and without hormonal contraception (HC) compared to controls with HC, measured by transvaginal ultrasound (TVUS). Summary answer AP with HC s…

Abstract Study question Comparison of uterine contractility (UC) in adenomyosis patients (AP) with and without hormonal contraception (HC) compared to controls with HC, measured by transvaginal ultrasound (TVUS). Summary answer AP with HC s…

Development of a multivariate prediction model based on MRI and clinical parameters for histological adenomyosis diagnosis. This single centre retrospective cohort study took place in the gynaecological department of a referral hospital. In…

Uterine peristalsis is the rhythmic wave-like motion of the subendometrial layer of the uterus. These contractions change throughout the menstrual cycle in terms of direction, frequency and amplitude, and can be analysed with various method…

Comparison of uterine contractility (UC) in adenomyosis patients (AP) with and without hormonal contraception (HC) compared to healthy controls with HC, measured by transvaginal ultrasound (TVUS). Ongoing multi-centre prospective observatio…

Comparison of uterine contractions via quantitative 2D transvaginal ultrasound measurements in women with adenomyosis compared to healthy controls. In this multicentre prospective observational cohort study, 29 women with adenomyosis with a…

Study Objective: Development of a prediction tool for histopathological adenomyosis diagnosis after hysterectomy based on MRI and clinical parameters. Design: Single-centre retrospective cohort study Setting: Gynaecological department of a …

INTRODUCTION: Magnetic resonance imaging (MRI) diagnosis of adenomyosis is considered the most accurate non-invasive technique, but remains subjective, with no consensus on which diagnostic parameters are most accurate. We aimed to systemat…