Vecellio M

ORCID: 0000-0002-8643-1316 · 1 paper in corpus

2016

The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression.

Annals of the rheumatic diseases ·doi:10.1136/annrheumdis-2015-207490

ObjectivesTo identify the functional basis for the genetic association of single nucleotide polymorphisms (SNP), upstream of the RUNX3 promoter, with ankylosing spondylitis (AS).MethodsWe performed conditional analysis of genetic associatio…