Yongchun Li

No ORCID on file · 1 paper in corpus

lab-animal 2022

M1 macrophage-derived extracellular vesicle containing tsRNA-5006c promotes osteogenic differentiation of aortic valve interstitial cells through regulating mitophagy

PeerJ ·doi:10.7717/peerj.14307

BACKGROUND: Osteogenic differentiation of aortic valve interstitial cells (AVICs) plays a key role in the calcific aortic valve disease progression. Extracellular vesicles (EVs)-derived from M1-polarized macrophages (M1-EVs) orchestrated in…