Sarah Brunty

ORCID: 0000-0001-7850-1807 · 6 papers in corpus · active 2019-2025

Study types

  • article 4
  • letter 1
  • review 1

Condition tags

  • endometriosis 6
  • infertility 2
  • chronic_pelvic_pain 1
article 2025
iScience ·doi:10.1016/j.isci.2025.112143

We recently showed that endometriotic peritoneal fluid (PF) altered the regulation of enhancer of zeste homolog 2 (EZH2) and H3K27me3. This study aimed to determine if PF by regulating EZH2/H3K27me3 modulated C-X-C chemokine receptor type 4…

article 2021
Frontiers in oncology ·doi:10.3389/fonc.2021.793297

Ovarian cancer is the 4th largest cause of cancer death in women. Approximately 10–15% of women of childbearing age suffer from endometriosis. Endometriosis is defined by the growth and presence of endometrial tissue (lesions) outside of th…

article 2021
International journal of molecular sciences ·doi:10.3390/ijms22073492

Activation of trimethylation of histone 3 lysine 27 (H3K27me3) by EZH2, a component of the Polycomb repressive complex 2 (PRC2), is suggested to play a role in endometriosis. However, the mechanism by which this complex is dysregulated in e…

review 2020
Annals of translational medicine ·doi:10.21037/atm-20-2449

Abstract: Endometriosis is a gynecological disorder that affects 176 million women worldwide and 1 in 10 females in the United States. Endometriosis most often affects women of child-bearing age, with most going undiagnosed. Endometriosis a…

article 2019
·doi:10.1096/fasebj.2019.33.1_supplement.680.8

Endometriosis is a complex disorder that afflicts many women with chronic pelvic pain and infertility. It is believed that polycomb group of proteins, such as enhancer of zeste homolog 2 (EZH2), which plays a major role in cancer, also migh…

letter 2019
Annals of translational medicine ·doi:10.21037/atm.2019.12.119

Endometriosis is a gynecological disease that affects 1 in 10 women worldwide and is characterized by the presence of lesions made up of endometrial cells (ECs) outside of the uterus. Symptoms associated with endometriosis include pain and …