Chen GH

ORCID: 0000-0002-7727-4662 · 1 paper in corpus

2026

Spermidine Targets Ovarian Granulosa Cells via Activating the FHC/SLC7A11 Axis to Regulate Iron Homeostasis and Ameliorate Iron Overload-Induced Ovarian Dysfunction

Antioxidants (Basel, Switzerland) ·doi:10.3390/antiox15050637

Females with iron overload suffer from follicular dysplasia, and effective therapeutic strategies for preserving fertility remain lacking. As a natural aliphatic polyamine, spermidine exerts antioxidant activity and plays an anti-ferroptosi…