Vargheese M Chennathukuzhi

No ORCID on file · 3 papers in corpus
lab-animal 2022
BMC cancer ·doi:10.1186/s12885-022-09280-2

BACKGROUND: Breast cancer is the most common malignancy in women, and is both pathologically and genetically heterogeneous, making early detection and treatment difficult. A subset of breast cancers express normal levels of REST (repressor …

lab-animal 2022
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2205524119

Uterine leiomyomas (UL) are benign tumors that arise in the myometrial layer of the uterus. The standard treatment option for UL is hysterectomy, although hormonal therapies, such as selective progesterone receptor modulators, are often use…

lab-animal 2008
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2008.08.008

Selective estrogen receptor modulators (SERMs) have the potential to treat estrogen sensitive diseases such as uterine leiomyoma and endometriosis, which are prevalent in reproductive age women. However, SERMs also increase the risk of deve…