Nila NN

ORCID: 0009-0006-2344-5709 · 1 paper in corpus

2026

Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study.

Biochemistry and biophysics reports ·doi:10.1016/j.bbrep.2026.102502

Aldo-keto reductase family 1 member C1 (AKR1C1) is a key enzyme involved in steroid hormone and xenobiotic metabolism and has been implicated in hormone-dependent cancers, chemoresistance, and inflammatory disorders. Genetic variation in AK…