Qingqing Huang

ORCID: 0000-0001-9160-0009 · 3 papers in corpus
article 2022
How does the extent of fibrosis in adenomyosis lesions contribute to heavy menstrual bleeding?
Reproductive medicine and biology ·doi:10.1002/rmb2.12442

Purpose: To investigate how the extent of fibrosis in adenomyosis lesions contributes to heavy menstrual bleeding (HMB). Methods: We recruited 57 women with histologically confirmed adenomyosis, 29 of whom reported moderate/heavy bleeding (…

article 2021
Changing prostaglandin E2 (PGE2) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE2 receptor EP2 and EP4
Reproductive medicine and biology ·doi:10.1002/rmb2.12426

Abstract Purpose We investigated the change, if any, in prostaglandin E2 (PGE 2 ) signaling in endometriotic lesions of different developmental stages in mouse. In addition, we evaluated the effect of treatment of mice with induced deep end…

article 2021
Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling
Reproductive medicine and biology ·doi:10.1002/rmb2.12423

Abstract Purpose While the prevailing view holds that the prostaglandin E2 (PGE 2 ) signaling plays a vital role in endometriosis, PGE 2 also is known to be anti‐fibrotic. We investigated the immunostaining of COX‐2, EP2, and EP4, along wit…