Yuan Zhu

No ORCID on file · 5 papers in corpus · active 2008-2025

Study types

  • article 2
  • other 2
  • preprint 1

Condition tags

  • endometriosis 4
other 2025
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis
Cellular signalling ·doi:10.1016/j.cellsig.2024.111523

Aberrant endometrial collagen I deposition during the implantation window impairs endometrial stromal cell (ESC) decidualization, which may contribute to lower pregnancy rate in endometriosis (EMs) patients with in vitro fertilization (IVF)…

article 2024
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis
Molecular human reproduction ·doi:10.1093/molehr/gaae042

Endometrial collagen I undergoes dynamic degradation and remodelling in response to endometrial stromal cell (ESC) decidualization and embryo implantation. However, excessive collagen I deposition in the endometrium during the implantation …

preprint 2023
Endometriotic Stromal Cell-Derived Exosomal miR-25-3p Induces Endometrial Collagen Ⅰ Deposition Impairing Decidualization And Embryo Implantation via Targeting PTEN in Endometriosis
·doi:10.2139/ssrn.4325256
article 2018
miR-137 Affects Vaginal Lubrication in Female Sexual Dysfunction by Targeting Aquaporin-2
·doi:10.1016/j.esxm.2018.09.002

INTRODUCTION: Female sexual dysfunction (FSD) is a common disease with serious potential hazards, but it has not received much attention. The pathogenesis of FSD is urgently needed for the diagnosis and treatment of FSD. AIM: To investigate…

other 2008
Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)
Journal of medicinal chemistry ·doi:10.1021/jm701080t

We have continued to explore the 3,3-dialkyl-5-aryloxindole series of progesterone receptor (PR) modulators looking for new agents to be used in female healthcare: contraception, fibroids, endometriosis, and certain breast cancers. Previous…