Yashiro Motooka

ORCID: 0000-0002-4230-7559 · 5 papers in corpus
2025
Cancer science ·doi:10.1111/cas.16412

BRCA1 is one of the causative genes for hereditary breast and ovarian cancer syndrome with a high risk of early-onset breast cancer. Whereas olaparib (OLA), an inhibitor of poly-ADP-ribose polymerase, has been applied as adjuvant therapy to…

2023
Genes and environment : the official journal of the Japanese Environmental Mutagen Society ·doi:10.1186/s41021-023-00258-5

Cancer is the primary cause of human mortality in Japan since 1981. Although numerous novel therapies have been developed and applied in clinics, the number of deaths from cancer is still increasing worldwide. It is time to consider the str…

2021
Journal of cancer prevention ·doi:10.15430/jcp.2021.26.4.244

Human epidemiological and animal studies have demonstrated that excess iron is a risk for cancer. The responsible mechanisms are: 1) increased intracellular iron catalyzes the Fenton reaction to generate hydroxyl radicals, leading to mutage…

other 2020
Redox biology ·doi:10.1016/j.redox.2020.101726

Ovarian endometriosis (OE) provides women of reproductive age with not only severe menstrual pain but also infertility and an increased risk for ovarian carcinogenesis. Whereas peritoneal endometriosis models have been developed with syngen…

article 2018
Gynecologic oncology reports ·doi:10.1016/j.gore.2018.01.010

•A patient had endometrioid adenocarcinoma arising from endometriosis in the canal of Nuck.•The tumor invaded muscles in the inguinal region.•She showed favorable prognosis by radical surgery and adjuvant chemotherapy.