Ogino S

ORCID: 0000-0002-3909-2323 · 3 papers in corpus
2024
The Cancer Spectrum Theory.
Cancer discovery ·doi:10.1158/2159-8290.cd-23-1494

SummaryBiological characteristics of tumors are heterogeneous, forming spectra in terms of several factors such as age at onset, anatomic spatial localization, tumor subtyping, and the degree of tumor aggressiveness (encompassing a neoplast…

2019
Discovery of common and rare genetic risk variants for colorectal cancer.
Nature genetics ·doi:10.1038/s41588-018-0286-6

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome…

2019
Plasma Biomarkers of Insulin and the Insulin-like Growth Factor Axis, and Risk of Colorectal Adenoma and Serrated Polyp.
JNCI cancer spectrum ·doi:10.1093/jncics/pkz056

BackgroundHyperinsulinemia, high insulin-like growth factor 1 (IGF1) levels, and low IGF binding protein 1 (IGFBP1) levels have been implicated in the relationship between obesity and increased risk of colorectal cancer (CRC). However, it r…