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ImportanceDietary supplements marketed for male fertility commonly contain folic acid and zinc based on limited prior evidence for improving semen quality. However, no large-scale trial has examined the efficacy of this therapy for improvin…
The recent discovery of microRNAs (miRNAs) in human reproductive tissues and cells indicates a possible functional role in reproductive function. However, the studies published to date in female reproductive tissues/cells and embryos are in…
Biological, genetic, and socio-demographic factors are all important in explaining reproductive behavior, yet these factors are typically studied in isolation. In this study, we explore an innovative sociogenomic approach, which entails inc…
ObjectiveTo evaluate the relationship between epigenetic patterns in sperm and fecundity.DesignProspective study.SettingAcademic andrology and in vitro fertilization laboratory.Patient(s)Twenty-seven semen samples from couples who conceived…
ObjectiveTo assess the effects of both male and female body mass index (BMI), individually and combined, on IVF outcomes.DesignProspective cohort study.SettingUniversity fertility center.Patient(s)All couples undergoing first fresh IVF cycl…
ObjectiveTo describe the influence of the TTTA aromatase polymorphism (TTTAn) on the relation between obesity and plasma estradiol (E(2)) in obese men.DesignA 2-year cohort study.SettingClinical research center.Patient(s)Severely obese men …
OBJECTIVES: To determine whether one to four cycles of ovulation induction with hMG and IUI or one cycle of IVF results in the highest pregnancy rate and is least expensive and whether published pregnancy rates for one to four cycles of hMG…