Neale BM

No ORCID on file · 3 papers in corpus · active 2013-2020
2020
The genetic architecture of sporadic and multiple consecutive miscarriage.
Nature communications ·doi:10.1038/s41467-020-19742-5

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies. Here we present the results of large-scale genetic association analyses with 69,054 cases from five different ancestries for sporadic miscarriage, 75…

2017
Phenome-wide heritability analysis of the UK Biobank.
PLoS genetics ·doi:10.1371/journal.pgen.1006711

Heritability estimation provides important information about the relative contribution of genetic and environmental factors to phenotypic variation, and provides an upper bound for the utility of genetic risk prediction models. Recent techn…

2013
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
Nature genetics ·doi:10.1038/ng.2711

Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype da…