Xi Shen

BACKGROUND: In assisted reproductive technology, preventing premature ovulation is crucial for achieving successful pregnancy outcomes. The traditional GnRH antagonist protocol is commonly used to suppress the luteinizing hormone (LH) surge…

BACKGROUND: In clinical practice, scheduling oocyte retrieval is a challenging issue that requires comprehensive consideration of factors such as the woman's age, ovarian response, hormone levels and other variables. Moreover, there is curr…

BACKGROUND: Clomiphene citrate effectively suppressed the negative feedback of estrogen on the hypothalamus and induces premature luteinizing hormone (LH) surge during controlled ovulation stimulation, while obese women often have impaired …

STUDY QUESTION: What are the odds of achieving pregnancy when adopting progestin-primed ovarian stimulation (PPOS)-related protocols combined with repetitive frozen-thawed transfer (FET) cycles in patients with different clinical characteri…

STUDY QUESTION: Which specific groups of women would not benefit from repeated frozen embryo transfers (FETs)? SUMMARY ANSWER: Women over 45 years of age should stop treatment after three FET attempts due to the absence of further benefits…

Object: Is it possible to use different progestins cotreatment with human menopausal gonadotrophin (hMG) in women with advanced endometriosis but normal ovulation during controlled ovarian hyperstimulation (COH) in vitro fertilization (IVF)…

PURPOSE: To explore the trends of oocyte and pregnancy outcomes over the ovulation trigger-OPU (oocyte pickup) time interval in four mainly used COH protocols. METHODS: This retrospective study was conducted between January 2013 and July 2…

Background: To investigate the optimal ovulation trigger-oocyte pickup (OPU) interval of a progestin-primed ovarian stimulation (PPOS) protocol. Method: Patients with normal ovarian reserve in their first PPOS OPU cycle were enrolled in thi…