Meekrathok P

ORCID: 0000-0003-3566-1231 · 1 paper in corpus

2025

FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy.

Nature communications ·doi:10.1038/s41467-025-56633-z

Protein O-GlcNAcylation is a post-translational modification coupled to cellular metabolic plasticity. Aberrant O-GlcNAcylation has been observed in many cancers including endometrial cancer (EC), a common malignancy in women. However, clin…