OBJECTIVE: Intraoperative frozen section examination is crucial for confirming the oncological safety of radical abdominal trachelectomy (RAT) for early-stage cervical cancer. This study evaluated the diagnostic accuracy of frozen section d…
Despite widespread cervical cancer (CC) screening programs, low participation has led to high morbidity and mortality rates, especially in developing countries. Because early-stage CC often has no symptoms, a non-invasive and convenient dia…
UNLABELLED: Ovarian cancer has a poor prognosis and is difficult to detect in early stages. Therefore, developing new diagnostic markers for early-stage ovarian cancer is critical. Here, we developed a diagnostic marker for early-stage ovar…
Precision medicine based on cancer genomics is being applied in clinical practice. However, patients do not always derive benefits from genomic testing. Here, we performed targeted amplicon exome sequencing-based panel tests, including 160 …
•Cervical cancer occurring in patients with OHVIRA syndrome is very rare.•This case reports on HPV-negative adenocarcinoma located in the nonvisible cervix.•Colposcopy and imaging are essential for cervical cancer with uterine malformation.…
症例は30歳代の女性で,20歳代より子宮内膜症で内服治療を受けていた.2005年頃より月経時に下血・腹痛を認め,近医にて直腸子宮内膜症(AVから約20cmの部位)が疑われ当科紹介となった.挙児希望にて保存的治療を継続し,2010年に症状が持続するために再度手術目的にて当科紹介となった.腹腔鏡下低位前方切除術を施行し,術中術後合併症も認めず術後11日目に退院した.病理組織検査では,直腸粘膜固有筋層内から粘膜固有層にかけて,子宮内膜様の腺構造と固有間質が島状に散見されendome…