Keller A

ORCID: 0000-0002-5361-0895 · 4 papers in corpus · active 2010-2021
2021
Scientific reports ·doi:10.1038/s41598-021-92901-w

Women undergoing infertility treatment are routinely subjected to one or more tests of ovarian reserve. Therefore, an adequate assessment of the ovarian reserve is necessary for the treatment. In this study, we aimed to characterize the pot…

2020
Nature communications ·doi:10.1038/s41467-020-19665-1

Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing wh…

2020
JAMA oncology ·doi:10.1001/jamaoncol.2020.0001

ImportanceThe overall low survival rate of patients with lung cancer calls for improved detection tools to enable better treatment options and improved patient outcomes. Multivariable molecular signatures, such as blood-borne microRNA (miRN…

2010
British journal of cancer ·doi:10.1038/sj.bjc.6605833

BackgroundScreening is an unsolved problem for ovarian cancer (OvCA). As late detection is equivalent to poor prognosis, we analysed whether OvCA patients show diagnostically meaningful microRNA (miRNA) patterns in blood cells.MethodsBlood-…