Kaylon L. Bruner‐Tran

article 2002

Differential regulation of the progesterone receptor (PR) by TCDD in isolated human endometrial stromal cells versus stromal-epithelial co-cultures

·doi:10.1016/s0015-0282(01)03017-5

review 2002

Experimental Endometriosis

Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02793.x

Endometriosis is a complex disease that can develop as a consequence of retrograde menstruation, occurring in association with the cyclic loss of endometrial tissue in primates and humans. In addition, progression of disease parallels a wom…

review 2002

Paracrine mediators of endometrial matrix metalloproteinase expression: potential targets for progestin-based treatment of endometriosis

Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02774.x

The endometrial lining of the human uterus is a highly specialized, steroid-sensitive tissue. Throughout the reproductive years, the endometrium undergoes dramatic cycles of growth, differentiation, and breakdown under the influence of ovar…

other 2002

Progesterone-mediated endometrial maturation limits matrix metalloproteinase (MMP) expression in an inflammatory-like environment: a regulatory system altered in endometriosis

Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2002.tb02764.x

The human endometrium exhibits regular cycles of growth, differentiation, and breakdown in response to changing levels of ovarian steroids. Following the tissue loss and repair processes of menstruation, rising levels of estradiol initiate …

article 2002

Steroid and Cytokine Regulation of Matrix Metalloproteinase Expression in Endometriosis and the Establishment of Experimental Endometriosis in Nude Mice

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2002-020418

The cyclic expression of matrix metalloproteinases (MMPs) by human endometrium has been suggested to play a role in the invasive process necessary to establish endometriosis. The ability of progesterone exposure to inhibit endometrial MMP-3…

article 2002

Uterine endometrial stability is dependent on the presence of both estrogen and progesterone

·doi:10.1016/s0015-0282(02)03817-7

article 2001

Steroidogenesis-inducing protein (SIP) stimulates endometrial matrix metalloproteinase-3 (MMP-3) expression and antagonizes progesterone-mediated suppression of this enzyme.

·doi:10.1016/s0015-0282(01)02151-3

article 2000

Establishment of Experimental Endometriosis by Eutopic or Ectopic Endometrial Tissue Acquired from Women with Endometriosis Cannot be Prevented by Progesterone Treatments

·doi:10.1016/s0015-0282(00)00779-2

review 1999

The Potential Role of Environmental Toxins in the Pathophysiology of Endometriosis

Gynecologic and obstetric investigation ·doi:10.1159/000052868

Environmental contaminants that are known to disrupt steroid action can influence the development of reproductive diseases. Our group has focused on whether 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or dioxin) can disrupt steroid regulation…