Fiona Simpkins

ORCID: 0000-0002-0840-2368 · 1 paper in corpus

article 2020

Synthetic-lethal interactions between ATR inhibition and functional genetic and proteomic biomarkers to predict responses in endometriosis-associated cancers.

·doi:10.1200/jco.2020.38.15_suppl.e18000

e18000 Background: Endometriosis is a common gynecologic disorder proven to be a precursor to several cancer types. We developed a potent and selective inhibitor (ATRN-119) of a critical DNA damage response (DDR) protein kinase: the ataxia …