Huntsman D

No ORCID on file · 11 papers in corpus · active 1999-2025

Study types

  • other 2
  • article 1
  • preprint 1

Condition tags

  • endometriosis 4
  • endometrioma 1
  • die_deep_infiltrating 1
2025
BMC cancer ·doi:10.1186/s12885-025-14384-6

BACKGROUND: With recent evidence that opportunistic salpingectomy is effective in preventing high grade serous carcinoma, it is imperative to consider the optimal use of this procedure. In this research, we investigated the opinions of obst…

2024
The Journal of molecular diagnostics : JMD ·doi:10.1016/j.jmoldx.2024.09.001

The low incidence of ovarian cancer (OC) dictates that any screening strategy needs to be both highly sensitive and highly specific. This study explored the utility of detecting multiple colocalized proteins or glycosylation epitopes on sin…

2023
Current oncology (Toronto, Ont.) ·doi:10.3390/curroncol30120741

Epithelial ovarian cancer (EOC) is a heterogeneous group of malignancies, including high-grade serous ovarian cancer (HGSC). HGSC is often diagnosed at advanced stages and is linked to TP53 variants. While BRCA variants elevate risk, most H…

2022
Current oncology (Toronto, Ont.) ·doi:10.3390/curroncol29070368

Individuals with proven hereditary cancer syndrome (HCS) such as BRCA1 and BRCA2 have elevated rates of ovarian, breast, and other cancers. If these high-risk people can be identified before a cancer is diagnosed, risk-reducing intervention…

other 2022
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.CCR-21-3817

PURPOSE: To identify molecular subclasses of clear cell ovarian carcinoma (CCOC) and assess their impact on clinical presentation and outcomes. EXPERIMENTAL DESIGN: We profiled 421 primary CCOCs that passed quality control using a targeted…

preprint 2021
·doi:10.1101/2021.05.20.445037

Abstract Endometriosis is a common, benign condition characterized by extensive heterogeneity in lesion appearance and patient symptoms. We profiled transcriptomes of 207,949 individual cells from endometriomata (n=7), extra-ovarian endomet…

2019
International journal of cancer ·doi:10.1002/ijc.32029

As a follow-up to genome-wide association analysis of common variants associated with ovarian carcinoma (cancer), our study considers seven well-known ovarian cancer risk factors and their interactions with 28 genome-wide significant common…

2014
Journal of the National Cancer Institute ·doi:10.1093/jnci/dju029

The Ovarian Task Force of the Gynecologic Cancer Steering Committee convened a clinical trials planning meeting on October 28-29, 2011, with the goals to identify key tumor types, associated molecular pathways, and biomarkers for targeted d…

2013
Nature communications ·doi:10.1038/ncomms2629

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovaria…

other 2012
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/IGC.0b013e318231f140

BACKGROUND: Inactivating somatic mutations in the ARID1A gene are described in a significant fraction of clear cell and endometrioid ovarian cancers leading to loss of the corresponding protein (BAF250a). Expression of BAF250a was examined …

article 1999
The American journal of pathology ·doi:10.1016/s0002-9440(10)65130-9

The transmembrane tyrosine kinase receptor c-met with its ligand, hepatocyte growth factor/scatter factor (HGF/SF), acts as a mitogen, motogen, and morphogen in many normal epithelia. HGF/SF-met signaling has also been implicated in neoplas…