Yao Xiong

ORCID: 0000-0002-7081-0805 · 14 papers in corpus · active 2015-2025

Study types

  • article 7
  • other 5
  • preprint 1
  • review 1

Condition tags

  • endometriosis 13
  • mesh:D004715 12
  • infertility 3
  • adenomyosis 1
preprint 2025
·doi:10.21203/rs.3.rs-7614122/v1
other 2025
American journal of physiology. Cell physiology ·doi:10.1152/ajpcell.00493.2024

Histone lactylation is crucial in a variety of physiopathological processes; however, the function and mechanism of histone lactylation in endometriosis remain poorly understood. Therefore, the objective of this investigation was to illumin…

other 2024
The Journal of endocrinology ·doi:10.1530/JOE-23-0319

The impaired endometrial receptivity is a major factor contributing to infertility in patients with endometriosis (EM), but the underlying mechanism remains unclear. Our study aimed to investigate the role of Kruppel-like factor 15 (KLF15) …

article 2022
BMC pregnancy and childbirth ·doi:10.1186/s12884-022-05276-9

BACKGROUND: Plenty of studies explored the most optimal treatment protocol for infertile women with adenomyosis in in-vitro fertilization (IVF) /intracytoplasmic sperm injection (ICSI), however, there is still no consensus on which treatmen…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00076-7

Results of previous epidemiology studies on BPA exposure and endometriosis (EMs) risk were inconsistent, and were limited by inappropriate control selection, incorrect BPA detection method, and the generalization of different subtypes of EM…

article 2020
Environmental pollution (Barking, Essex : 1987) ·doi:10.1016/j.envpol.2020.115748

Overexpression of estrogen receptor β (ERβ) in endometrium contributes to endometriosis (EM) pathogenesis. Trimethylation of the H3 lysine (K) 4 (H3K4me3) in promoters is strongly correlated with gene expression. This study aimed to explore…

article 2020
Journal of molecular endocrinology ·doi:10.1530/jme-20-0193

The aberrant histone methylation patterns contribute to the pathogenesis of endometriosis (EM). Mixed lineage leukemia 1 (MLL1), a histone methyltransferase, is crucial for gene expression by catalyzing the trimethylation of histone 3 lysin…

review 2019
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2019.1590546

Endocrine-disrupting chemicals (EDCs) are suspected to be associated with endometriosis (EMs). This study aimed to synthesize published data and evaluate the relationship between four classic EDCs exposure and the risk of EMs. A systematic …

article 2017
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0643

Endometriosis is a benign gynecological disease that shares some characteristics with malignancy like migration and invasion. It has been reported that both hypoxia-inducible factor-1α (HIF-1α) and autophagy were upregulated in ectopic endo…

other 2016
Molecular human reproduction ·doi:10.1093/molehr/gaw025

STUDY HYPOTHESIS: Do estrogen and Wnt/β-catenin signaling promote vascular endothelial growth factor (VEGF) expression in endometriosis and how? STUDY FINDING: 17β-Estradiol (E2)-drives β-catenin triggered up-regulation of VEGF in effector…

other 2016
Human Reproduction ·doi:10.1093/humrep/dew081

STUDY QUESTION: How does hypoxia promote growth of lesions in the development of endometriosis? SUMMARY ANSWER: Hypoxia induces the epithelial-mesenchymal transition (EMT) of endometrial cells, resulting in changes in cellular characterist…

article 2016
Biology of reproduction ·doi:10.1095/biolreprod.115.135574

Extracellular matrix remodeling is necessary for ectopic endometrium implantation. Many studies have shown an increased expression of matrix metalloproteinase 9 (MMP9) in the ectopic endometrium of endometriosis. However, the signaling path…

article 2015
Reproduction (Cambridge, England) ·doi:10.1530/rep-15-0371

Endometriosis is an estrogen-dependent disease that involves the adhesion, invasion, and angiogenesis of endometrial tissues outside of the uterine cavity. We hypothesized that a link exists between estrogen and beta-catenin (β-catenin) sig…

article 2015
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115607999